Protesters took to streets in several cities including Karak, Tafileh, Salt, Ma’an and Irbid after Friday prayers.
Citizens of Tafileh demanded the implementation of reforms promised by the government.
In Karak, hundreds of demonstrators urged the government to end the mounting “security pressures” on Jordanian people and protesters.
Chanting anti-government slogans, protesters in Tafileh announced their support for a nationwide strike by Jordanian teachers who demand better pay and full annual bonuses.
Most of the country's 1.4 million public schoolchildren are staying at home as a majority of the nearly 120,000 teachers have kept away from the kingdom's 3,370 public schools since early February.
Jordanians have been holding street protests since January 2011, demanding political reforms, including the election of the prime minister by popular vote and an end to corruption.
Since the beginning of protest rallies, Jordanian ruler King Abdullah II has sacked two prime ministers in a bid to avoid more protests. Khasawneh, a judge at International Court of Justice, became Jordan's third premier this year.
The king has also amended 42 articles in the 60-year-old constitution, giving parliament a stronger role in decision-making but the changes have failed to convince people.