Nabil Shaath and Othman Abu Gharbieh arrived in Gaza to take part in talks with members from nationalist and Islamic political factions.
"We hope it gives a push to Palestinian reconciliation," Shaath told Ma'an. "Both reconciliation and the organizational position [of Fatah] are the priorities of the visit."
"We hope to end the visit with positive results for the Gaza Strip," he added.
Last month, Fatah and Hamas agreed to set a three-month timetable for forming a unity government.
Establishing a unity government and holding elections was one of the aims of a reconciliation deal the two nationalist movements signed two years ago, but it has never been implemented.